Menstrual Magic ® Safety/Toxicity Study

SUMMARY

Acute Oral Toxicity Study of Proprietary Essential Oil Blend in Sprague Dawley rats was performed in compliance with the OECD guidelines for testing of chemicals, Section 4, No. 420-Acute Oral Toxicity-Fixed Dose Method, adopted 17 December 2001.

A Sighting Study was performed prior to main study. In the sighting study, one female rat was administered the test article, as such (without dilution), at the dose of 5000 mg/Kg body weight. No mortality or signs of toxicity were encountered in this study.

Hence in the Main Study, the test article was administered orally by gavage as a single dose to a group of four female and five male rats at the dose of 5000 mg/kg.

Proprietary Essential Oil Blend did not cause any mortality in rats treated at 5000 mg/Kg following dosing and during the observation period of 14 days post-dosing. No abnormal clinical signs were observed in treated rats throughout the observation period. It did not induce any adverse effects on the body weight gain of rats treated at 5000 mg/Kg. No gross pathological alterations were detected in the treated rats at terminal necroscopy.

Based on these results, and according to the “Globally Harmonised System (GHS) for classification of chemicals which cause acute toxicity, OECD series on testing and assessment, Number 23; Harmonised Integrated Classification System for human Health and Environmental Hazards of Chemical Substances and Mixtures [ENV / JM / MONO (2001) 6]”, the test article Proprietary Essential Oil Blend has to be classified in GHS Category 5 / Unclassified for the obligatory labeling requirement for oral toxicity.    For complete study, contact us at info@naturalmiracles.net.